Alzheimer’s Disease, Dementia and Periodontal Disease

Posted on Aug 15, 2024 by William J. Claiborne, DDS MS

In information posted on the web site of the Alzheimer’s Association (www.alz.org),

“A recent analysis led by National Institute on Aging (NIA) scientists suggests that the bacteria associated with periodontal disease that causes the chronic inflammation are also associated with the development of Alzheimer’s disease and related dementias, especially vascular dementia.”

https://www.alz.org/co/news/oral-health-and-alzheimers-risk#:~:text=A%20recent%20analysis%20led%20by,related%20dementias%2C%20especially%20vascular%20dementia.

Is there a more dreaded disease today than Alzheimer’s? Not only is the individual effected, entire families are devastated when dealing with a loved one’s diagnosis.

In the U.S., it is the 6th leading cause of death.

https://www.alzheimers.net/resources/alzheimers-statistics/

By the year 2025, the number of people 65 and older with Alzheimer’s disease is expected to reach 7.1 million people, a 27% increase from the 5.6 million over the age of 65 in 2019.

In 2020, it was estimated that 11.6% of North Carolina adults aged 65 and over had some level of the disease. Currently, 10% of American adults 65 and over have Alzheimer’s disease. For people ages 85 and older, this increases to 32%.
By 2060, nearly 1 in 4 Americans will be 65 years and older with seniors over age 85 having tripled.

https://www.alz.org/media/Documents/alzheimers-facts-and-figures.pdf

As a periodontist in Asheville NC, I’ve been following the findings related to Alzheimer’s disease and periodontal disease. Yes, the connection between the two seems far-fetched, but research is showing there is a correlation.

First, allow me to explain periodontal (gum) disease. Gum disease is an inflammatory disease that attacks gum tissues, teeth, and the structures that support them. It is the nation’s leading cause of adult tooth loss. In addition to the problematic oral symptoms associated with gum disease, research has shown that the infectious bacteria are able to activate the development (or worsen the progress) of other diseases.

Because the bacteria of gum disease are able to enter the bloodstream through weakened oral tissues, studies have connected them to serious reactions elsewhere in the body. Some of these lead to the formation of cancer (oral, throat, pancreatic, lung) and some activate conditions such as diabetes and arthritis.

While the statistics of aging adults increase, nearly half of the adult population has some level of gum disease, over 47%. As a periodontal specialist in Western NC, I believe the high prevalence of gum disease among U.S. adults may be, in part, due to the assumption, “if it doesn’t hurt, nothing is wrong”. People also tend to brush off some symptoms as “normal,” such as seeing blood in the sink when brushing teeth.

Although symptoms of gum disease may include tender gums that bleed when brushing, gum disease can begin without any obvious signs. One study included over 8,200 adult at an average age of 63 at the study’s onset. The findings showed an increased propensity for developing dementia for participants who had severe gum disease and missing teeth.

Having no natural teeth was associated with a 26% increased risk. At the end of the study:

• 14% of individuals with healthy gums and all their teeth at the start of the study developed dementia by the end of the study
• 18% of participants with mild gum disease developed dementia
• 22% with severe gum disease (periodontitis) developed dementia
• 23% of those with no remaining teeth developed dementia

Eighteen years later, a follow-up study found those who had severe gingivitis in addition to tooth loss had a 22% higher risk for developing Alzheimer’s disease or dementia.

What researchers found is the bacteria present in periodontal disease are able to travel through the mucous membranes of the mouth to the brain. This is believed to cause potential brain damage.

https://psychcentral.com/news/2020/07/30/gum-disease-may-be-linked-to-later-dementia/158497.html?MvBriefArticleId=25473

Now, more than ever, maintaining a healthy smile is important for every adult. If you suspect you have gum disease (gums that bleed when brushing, tender or swollen gums, gums that have reddened or receded from teeth), be seen by a periodontist. This disease will only worsen without treatment.

Be committed to having excellent oral health as and make it a priority as an important part of your overall health. For a consultation to discuss how we can help you achieve optimal oral health, call 828-274-9440.

In addition to the treatment of all stages of gum disease and the reshaping of gum tissues, a periodontist is a specialist in the placement of dental implants. If you have lost teeth, dental implants are the ideal tooth replacement option.

Also, please know that our Asheville periodontal dental office offers many comfort options, including Oral and I.V. sedation. Oral sedation is a pill that helps patients relax. I.V. sedation (also known as ‘twilight sleep’) places the patient in a deeper sleep state and erases memory of the procedure. It is administered by a doctor of anesthesiology for optimal comfort and safety.